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Clinical trials for Fresh Frozen Plasma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    60 result(s) found for: Fresh Frozen Plasma. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2009-016709-41 Sponsor Protocol Number: FIB692 Start Date*: 2010-01-26
    Sponsor Name:NHS Lothian [...]
    1. NHS Lothian
    2. University of Edinburgh
    Full Title: Coagulopathy during surgery for the repair of Extent 4 Thoraco-Abdominal Aortic Aneurysms - feasibility study of the use of Fibrinogen Concentrate by infusion in place of Fresh Frozen Plasma.
    Medical condition: Coagulation disturbance during thoracoabdominal aneurysm repair.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-000177-39 Sponsor Protocol Number: Linea7-2013/06-APPEAR Start Date*: 2014-07-17
    Sponsor Name:IRCCS Policlinico San Donato
    Full Title: Albumin vs. Plasma for PEdiAtric pRiming (APPEAR) trial
    Medical condition: Congenital cardiac diseases needing surgical correction requiring intervention with extracorporeal circulation
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-005653-37 Sponsor Protocol Number: ICH-VKA Start Date*: 2009-05-29
    Sponsor Name:Universityhospital of Heidelberg
    Full Title: Multicenter, prospective randomized trial on the use of prothrombin complex and fresh frozen plasma in patients with intracerebral hemorrhage related to vitamin K antagonists (VKA)
    Medical condition: Intracerebral hemorrhage (ICH) in patients related to vitamin K antagonists
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10022754 Intracerebral hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Suspended by CA) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-000444-22 Sponsor Protocol Number: NL75930.078.20 Start Date*: 2021-04-07
    Sponsor Name:Erasmus MC
    Full Title: Differences in coagulation between fresh frozen plasma and Solventdetergent plasma in pediatric congenital heart surgery
    Medical condition: coagulation in pediatric cardiac surgery
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000452-28 Sponsor Protocol Number: VIPER-OCTA Start Date*: 2014-11-05
    Sponsor Name:Section for Transfusion Medicine, Capitol Region Blood Bank
    Full Title: Vasculopathic Injury and Plasma as Endothelial Rescue – OCTAplas trial
    Medical condition: patients undergoing emergency surgery for thoracic aortic dissections
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004848 10009789 Coagulation factors decreased LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-000449-11 Sponsor Protocol Number: EP250567 Start Date*: 2012-03-01
    Sponsor Name:Eero Pesonen
    Full Title: Heparin dose (300 IU/kg vs. 600 IU/kg) in coroanry artery bypass grafting
    Medical condition: Patients undergoing elective coronary artery bypass grafting
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10068176 Coronary artery bypass graft LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001936-86 Sponsor Protocol Number: COMET Start Date*: 2020-10-19
    Sponsor Name:Hannover Medical School
    Full Title: A prospective, randomized, open label Phase 2 clinical trial to evaluate superiority of anti-SARS-CoV-2 convalescent plasma versus standard-of-care in hospitalized patients with mild COVID-19
    Medical condition: Hospitalized patients with mild SARS-CoV-2 infection (WHO R&D Blueprint Ordinal Scale for Clinical Improvement = 3 or 4)
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004862 10084272 SARS-CoV-2 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004068-74 Sponsor Protocol Number: ZEPLAST-PED Start Date*: 2019-09-26
    Sponsor Name:I.R.C.C.S. POLICLINICO SAN DONATO
    Full Title: ZEro_PLASma Trial in small infants undergoing cardiac surgery
    Medical condition: Congenital heart disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000390-22 Sponsor Protocol Number: TV001 Start Date*: 2005-04-07
    Sponsor Name:Turku University Hospital
    Full Title: Antikoagulanttihoito varfariinilla sydäntahdistimen asennuksen yhteydessä
    Medical condition: The study population will consist of patients admitted for an elective implantation of a pacemaker or an arrhythmia device. The underlying medical conditions warranting the implantation of the devi...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003684-19 Sponsor Protocol Number: 15-163 Start Date*: 2018-02-08
    Sponsor Name:RWTH Aachen, represented by the Rector, himself represented by the Dean of the Medical Faculty
    Full Title: Xenon-anesthesia on patients undergoing major liver-resection: randomized controlled trial
    Medical condition: post-resectional liver failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-001697-58 Sponsor Protocol Number: 2128/2021 Start Date*: 2022-12-20
    Sponsor Name:Medical University of Vienna
    Full Title: An investigation of clinical outcomes and inflammatory response to heparin free extracorporeal membrane oxygenation support during clinical lung transplantation – a prospective double-blind randomi...
    Medical condition: Intraoperative extra-corporeal membrane oxygenation during lung transplantation for end-stage lung disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000703-24 Sponsor Protocol Number: 1175-2017 Start Date*: 2017-11-17
    Sponsor Name:Medical University of Vienna; Department of Surgery; Division of Transplantation
    Full Title: Treatment of anemia with intravenous iron in patients listed for orthotopic liver transplantation
    Medical condition: iron deficiency anemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004139-29 Sponsor Protocol Number: RETIC Start Date*: 2011-12-06
    Sponsor Name:Medizinische Universität Innsbruck / UK für Anästhesie und Intensivmedizin & UK für Allgem. u. Chirurg. Intensivmedizin
    Full Title: RETIC trial: Reversal of Trauma Induced Coagulopathy by using Coagulation factor concentrates or Fresh frozen Plasma
    Medical condition: Major trauma (Injury Severity Score, ISS >15), clinical signs/risk of blood loss and coagulopathy as measured by rotational thrombelastometry (ROTEM)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10018988 Haemorrhage NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-003041-41 Sponsor Protocol Number: 012507 Start Date*: 2018-11-16
    Sponsor Name:Queen Mary University of London
    Full Title: A pragmatic pilot randomised controlled trial of Prothrombin Complex Concentrate (PCC) versus Fresh Frozen Plasma (FFP) in adult patients who are undergoing Heart Surgery
    Medical condition: Major bleeding during cardiac surgery not related to vitamin K antagonists
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10051536 Intraoperative bleeding LLT
    20.1 100000004863 10036277 Postoperative bleeding LLT
    21.1 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-001163-20 Sponsor Protocol Number: 995 Start Date*: 2017-09-25
    Sponsor Name:Biotest AG
    Full Title: A randomized, active-controlled, multicenter, phase III study investigating efficacy and safety of intra-operative use of BT524 (human fibrinogen concentrate) in subjects undergoing major spinal or...
    Medical condition: Elective spinal or abdominal surgery with expected major blood loss
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10051125 Hypofibrinogenaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) ES (Ongoing) CZ (Completed) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-003895-21 Sponsor Protocol Number: 997HA309 Start Date*: 2020-11-01
    Sponsor Name:Biogen MA Inc
    Full Title: A Randomized, Open-Label Study to Evaluate the Pharmacokinetics and Safety of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc; BIIB031) Manufactured at 15K Scale and at Different Vial Strengths...
    Medical condition: Hemophilia A
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2012-005511-11 Sponsor Protocol Number: SPON1155-12 Start Date*: 2013-05-07
    Sponsor Name:RACD Cardiff University
    Full Title: Fibrinogen concentrate versus placebo for treatment of postpartum haemorrhage: a prospective double blind randomised control trial
    Medical condition: Postpartum haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    14.1 10036585 - Pregnancy, puerperium and perinatal conditions 10036294 Postpartum haemorrhage (primary) LLT
    14.1 10036585 - Pregnancy, puerperium and perinatal conditions 10043454 Third-stage postpartum haemorrhage LLT
    14.1 10036585 - Pregnancy, puerperium and perinatal conditions 10036417 Postpartum haemorrhage PT
    14.1 10036585 - Pregnancy, puerperium and perinatal conditions 10043449 Third stage postpartum haemorrhage PT
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002059-41 Sponsor Protocol Number: F7Trauma-1711 Start Date*: 2005-07-07
    Sponsor Name:Novo Nordisk A/S
    Full Title: A multi-center, randomized, double-blind, parallel group, placebo controlled trial to evaluate the efficacy and safety of activated recombinant factor VII (rFVIIa/NovoSeven®/NiaStase®) in severely ...
    Medical condition: Traumatic Hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    8.0 10053476 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) BE (Completed) GB (Completed) ES (Completed) CZ (Completed) IT (Completed) FI (Completed) SE (Completed) PT (Prematurely Ended) SI (Completed) GR (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2009-015086-31 Sponsor Protocol Number: Ten03 Start Date*: 2010-03-16
    Sponsor Name:Bio Products Laboratory Limited
    Full Title: Ten03: A Phase III Open, Multicentre Study to Investigate the Safety and Efficacy of BPL’s High Purity Factor X in the treatment of the Factor X Deficient Subjects Undergoing Surgery
    Medical condition: Factor X Deficiency
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003575-38 Sponsor Protocol Number: 071101 Start Date*: 2015-01-07
    Sponsor Name:Baxalta Innovations GmbH
    Full Title: A PHASE 3 PROSPECTIVE, MULTICENTER STUDY TO EVALUATE EFFICACY AND SAFETY OF rVWF WITH OR WITHOUT ADVATE IN ELECTIVE SURGICAL PROCEDURES IN SUBJECTS WITH SEVERE VON WILLEBRAND DISEASE
    Medical condition: Hereditary severe von Willebrand Disease in adult patients who will undergo major and minor elective surgical procedures
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004850 10055168 Von Willebrand's factor deficiency LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed) IT (Completed) CZ (Completed) GB (Completed) NL (Completed) ES (Completed) DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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